HyaluronDase 1500 UI is a freeze-dried hyaluronidase powder designed to correct and remove defects resulting from the administration of hyaluronic acid. The hyaluronidase enzyme, through its depolymerizing effect, dissolves the chemical bond (cross-linking) of hyaluronic acid molecules, accelerating their biodegradation. This preparation effectively dissolves subcutaneous nodules and excessively administered hyaluronic acid fillers, reversing negative consequences and restoring natural appearance.

Key Features and Benefits:

Effective Hyaluronidase Enzyme:

• Depolymerizing Effect: Hyaluronidase dissolves chemical bonds in cross-linked hyaluronic acid, breaking down acid molecules and speeding up their biodegradation.
• Corrects Overcorrection: Efficiently removes excessive amounts of hyaluronic acid, addressing overcorrection issues.
• Dissolves Subcutaneous Nodules: Targets long-lasting lumps or irregularities at the site of acid implantation, ensuring a smoother skin texture.
• Prevents Filler Displacement: Corrects undesirable filler displacement and visibility due to shallow deposition of hyaluronic acid.

Indications:

• Overcorrection of Hyaluronic Acid: Removes excessive amounts of administered hyaluronic acid.
• Irregularities at Injection Site: Addresses long-lasting lumps or irregularities.
• Filler Displacement: Corrects undesirable filler displacement.
• Accidental Administration: Prevents embolism and necrosis caused by accidental administration into an artery or vein.
• Visible Filler: Corrects undesirable visibility of the filler due to too shallow deposition.
• Chronic Swelling: Alleviates chronic swelling due to vessel compression or water retention.
• Intolerance: Suitable for patients intolerant to hyaluronic acid or cross-linking agents.

Active Ingredients:

• Hyaluronidase 1500 IU: Effective enzyme for breaking down hyaluronic acid.
• Mannitol: Enhances product stability and effectiveness.

How to Use:

1. Activation: Add 9 ml of injectable saline to the product.
2. Preparation: Combine with physiological saline to obtain 10 ml of hyaluronidase, providing 150 units in 1 ml.
3. Application: Apply topically 0.03-0.05 ml per spot.
4. Caution: Do not combine with other active substances.

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